7AlphaC4 (7 alpha-hydroxy-4-cholesten-3-one)-994

Test info

  
7AlphaC4 (7 alpha-hydroxy-4-cholesten-3-one)
  
994
  
LAB994
  
MSO
  
7AC4
7C4
Bile Acid Diarrhea (BAD) marker
Bile Acid Malabsorption (BAM) marker
Bile Acid precursor or intermediate
Bile Acid Synthesis surrogate
  

Serum 7AlphaC4 is a surrogate measure of stool bile acids (BA) and elevated levels may be diagnostic for bile acid malabsorption (BAM), also known as bile acid diarrhea (BAD)

  

Please note that this 7AlphaC4 test is for Bile Acid Malabsorption/Diarrhea. For cholestasis of pregnancy, Bile Acids, Fractionated and Total, LC/MS-MS [503640] is a different test.

Specimen

  

Sample collection in the morning after overnight fast is recommended.

  
Serum
  
0.5 mL
  
0.4 mL
  

Immediately following collection, mix sample thoroughly by gently inverting 5 times

  
  1. Allow sample to clot
  2. Spin  within two (2) hours of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
  4. Freeze
  
EDTA plasma; Heparin plasma
  

Lavender (EDTA), 4mL

Dark green heparin

 

  

Frozen (preferred) - 9 days

Freeze/thaw cycle - stable x6

Refrigerated - 9 days

Ambient - 1 day

 

  

Incorrect sample type

Performance

  
LabCorp (520550); R-NX
  
10 days
  

Tandem Mass Spectrometry (LC-MS/MS)

Clinical and Interpretive info

  

1.8 - 57 ng/mL

Billing

  
82542

Tracking

  
04/12/2024
  
04/12/2024