Variability in response (efficacy and toxicity) to 5-fluorouracil (5-FU) chemotherapy has been linked to the rate-limiting enzyme in the drug's catabolic pathway, known as dihydropyrimidine dehydrogenase (DPD)

This procedure will only detect the presence of the wild type or mutant allele for the DPD IVS14+1G>A mutation

Lavender (EDTA), 10mL

Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting

Lavender (EDTA), 10mL

Yellow ACD (A or B)

Immediately following collection, mix by inverting 8 - 10 times to prevent clotting

Yellow ACD (A or B)

Molecular Medicare billing request

• Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
• All information requested is required in order for your request to be completed

Ambient (preferred)

Refrigerated

• Frozen specimen
• Hemolysis
• Improper container
• Quantity not sufficient for analysis

Polymerase chain reaction (PCR), restriction enzyme digestion and gel electrophoresis

An interpretive report will be provided

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

• Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
• All information requested is required in order for your request to be completed

Molecular Medicare billing request