5' Nucleotidase-994
Test info
5' Nucleotidase
994
LAB994
MSO
5' nucleotidase is used to investigate the origin of increased serum alkaline phosphatase. It is a liver-related enzyme used to work up cholestatic/biliary obstruction. It parallels the increases of alkaline phosphatase and leucine aminopeptidase in hepatobiliary diseases, but is not usually elevated in skeletal disorders such as Paget disease of bone. It is increased with metastatic neoplasia in liver and in primary biliary cirrhosis, biliary obstruction from calculi and tumor.
Specimen
Serum
1.0 mL
0.2 mL
Submission of the minimum volume does not allow for repeat testing
Submission of the minimum volume does not allow for repeat testing
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
EDTA plasma
Heparin plasma
Heparin plasma
Red:
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer the serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
Dk green/lavender:
- Spin within two (2) hours of sample collection
- Transfer the plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as either EDTA or Heparin plasma
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
- Hemolysis
Performance
LabCorp Burlington (001701): R-NX
Mo, We, Fr
1 - 3 days
Kinetic - 340 nm
Clinical and Interpretive info
| Age | Male IU/L | Female IU/L |
| 0 - 1 y | 0 - 6 | 0 - 18 |
| 2 - 12 y | 0 - 7 | 0 - 7 |
| 13 - 17 y | 0 - 5 | 0 - 5 |
| 18 - 30 y | 0 - 5 | 0 - 7 |
| 31 - 50 y | 0 - 10 | 0 - 10 |
| 51 - 70 y | 0 - 11 | 0 - 11 |
| 71 - 80 y | 0 - 13 | 0 - 13 |
| >80 y | 0 - 18 | 0 - 15 |
Billing
83915
Result 1690-7
Tracking
05/21/2019
12/21/2023
12/21/2023