Thiopurine Methyltransferase (TPMT) and Nudix Hydrolase (NUDT15) genotyping-994

Test info

  
Thiopurine Methyltransferase (TPMT) and Nudix Hydrolase (NUDT15) genotyping
  
994
  
LAB994
  
MSO
  
6-mercaptopurine, 6-thioguanine, and azathioprine
  
Genotyping of TPMT and NUDT15, both of which affect metabolism of thiopurine drugs
  

Predicting potential for toxicity to thiopurine drugs (6-mercaptopurine, 6-thioguanine, and azathioprine)

Specimen

  
EDTA whole blood
  
  
3.0 mL
  
0.4 mL
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Lavender (EDTA), 4mL

  

Ambient (preferred) - 9 days

Refrigerated - 30 days

  
2 weeks

Performance

  
Mayo Clinic Laboratories (PTNUQ): R-NX
  
Mo - Fr
  
4 days
  

Real-Time Polymerase Chain Reaction (PCR) With Allelic Discrimination Analysis

Clinical and Interpretive info

  

An interpretive report will be provided

Billing

  
0034U
  
No

Tracking

  
05/23/2019
  
04/12/2022
  
04/12/2022