Neuromyelitis Optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, spinal fluid-12780

Test info

  
Neuromyelitis Optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, spinal fluid
  
12780
  
LAB12780
  
NMOFC
  
AQP
AQP4
Aquaporin
Devic's Antibody
NMO (Neuromyelitis Optica)
NMO-IgG
NMO/AQ
Optic Neuritis Ab
Transverse Myelitis Antibody
Vision Loss Antibody
  
Test will reflex to a titer, if indicated, at an additional charge
  
  • Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
  • Diagnosis of autoimmune AQP4 channelopathy
  • Distinguishing NMOSD from multiple sclerosis early in the course of disease

Specimen

  
Cerebrospinal fluid (CSF)
  

Sterile vial

  
3.0 mL
  
2.0 mL
  

Sterile vial

  

Refrigerated (preferred) - 28 days

Frozen - 28 days

Ambient - 72 hours

  
28 days

Performance

  
Mayo Clinic Laboratories (NMOFC): R-MM
  
Mo, Tu, Th
  
3 - 6 days
  

Flow Cytometry

Clinical and Interpretive info

  

Negative

  
A negative result does not exclude a diagnosis of neuromyelitis optica spectrum disorder (NMOSD). Recommend serum be tested if CSF tests negative and neuromyelitis optica spectrum disorder is suspected. AQP4-IgG antibodies may drop below detectable levels

Billing

  
86053
86053 - NMO/AQP4-IgG FACS titer (if appropriate)
  
17027437
17028488 - Titer (if indicated)
  
308605303
308605300 - Titer (if indicated)

Tracking

  
08/19/2015
  
12/27/2023
  
12/27/2023