DNA double-stranded (dsDNA) antibodies by Crithidia luciliae IFA-605

Test info

  
DNA double-stranded (dsDNA) antibodies by Crithidia luciliae IFA
  
605
  
86225.0
  
DNA
  
Anti-DNA
Anti DNA
Anti-ds DNA
Anti-native DNA
DNA
Double stranded DNA antibody
DS DNA
Native DNA antibody
  
  • Screening performed at 1:10 dilution
  • Titers performed - 1:20, 40, 80, 160, 320 and 640
  

Antibodies to native, double-stranded DNA (anti-nDNA) are found in up to 60% of patients with SLE, in almost all cases of lupus nephritis, and can be found in rheumatic diseases.

Specimen

  
Serum
  
  
1.0 mL
  
0.3 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  

Red serum vial/tube - 5 mL

Red/grey serum separator (SST) vial/tube, 10 mL

  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a False bottom plasma/serum transport vial/tube (AHL), labelled as serum, within two (2) hours of sample collection
  

False bottom plasma/serum transport vial/tube (AHL)

Red/grey serum separator (SST) vial/tube, 10 mL

  

Refrigerated (preferred) - 7 days
Frozen (OK)

  
  • Improper labels (unlabeled or mislabeled)
  • Hemolysis (some procedures)
  • Improper anticoagulant or ratio
  • Delay in transport
  • Improper storage temperature affecting results
  • Improper container
  • Leaking container resulting in compromised specimen
  • Quantity not sufficient (QNS)

Performance

  
AHL - Immunology: I
  
Mo - Fr
  
1 - 2 days
  

DNA Double-Stranded (dsDNA) Antibodies by Crithidia luciliae IFA, IgG, serum

Clinical and Interpretive info

  

Negative

  

The titer of the anti-nDNA may decrease with successful therapy and increases in acute recurrence of the disease.

Screening performed at 1:10 dilution. Titers performed - 1:20, 40, 80, 160, 320 and 640.

Billing

  
86225
86256 (if appropriate)

Tracking

  
11/30/2001
  
01/31/2022
  
01/24/2024