Inflammatory Bowel Disease (IBD)

Alphabetical Test listing

Inflammatory Bowel Disease (IBD)-13541

  
Inflammatory Bowel Disease (IBD)
  
13541
  
LAB13541
  
IBD
  
Bowel disease
Crohn's disease
Ulcerative colitis
  

Rule out Crohn's disease and ulcerative colitis.

  
Serum
  
Red
  

Gold SST

  
1.5 mL
  
0.7 mL
Note: This volume does not allow for repeat testing
  

SST - spin

Red - spin and separate.

  

Serum separator (SST) tube

LabCorp 12mL plastic transport tube labelled as serum

  

Refrigerated

  

Specimen should be free of bacterial contamination, hemolysis, and lipemia.

  
LabCorp Burlington (164830): R-LC
  
2 - 9 days
  

Atypical ANCA: Indirect fluorescent antibody (IFA)

Saccharomyces cerevisiae, IgA and IgG: Enzyme immunoassay (EIA)

  

Saccharomyces cerevisiae, IgA: negative: < 20.0

Saccharomyces cerevisiae, IgG:
Equivocal: 20.1 - 24.9
positive: ≥ 25.0

Atypical antineutrophil cytoplasmic antibodies: negative: < 1:20

  

IgA and IgG antibody testing for S. cerevisiae is useful adjunct testing for differentiating Crohn's disease and ulcerative colitis.  Nearly 80% of Crohn's disease patients are positive for either IgA or IgG.  In ulcerative colitis, less than 15% are positive for IgG, and less than 2% are positive for IgA.  Fewer than 5% of healthy controls are positive for either IgG or IgA antibody, and no healthy controls had antibody for both.  The atypical ANCA pattern has been observed in a significant percentage of patients with ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis.

  
86671 x 2
86256
  
Result 49503-6
  
04/08/2019
  
05/20/2019