NASH FibroSure Plus

Alphabetical Test listing

NASH FibroSure Plus-994

  
NASH FibroSure Plus
  
994
  
LAB994
  
MSO
  
Fatty liver disease
Nonalcoholic fatty liver disease
Noninvasive liver biopsy
Steatohepatitis
NAFLD
  
Fibrosis Score
Fibrosis Stage
Steatosis Score
Steatosis Grade
NASH Score
NASH Grade
Alpha 2-Macroglobulins, Qn
Haptoglobin
Apolipoprotein A-1
Bilirubin, Total
GGT
ALT (SGPT) P5P
AST (SGOT) P5P
Cholesterol, Total
Glucose, Serum
Triglycerides
Interpretations
  

This test is a noninvasive assessment of liver status in patients with nonalcoholic fatty liver disease (NAFLD). Quantitative results of 10 biochemicals in combination with age and gender are analyzed using a computational algorithm to provide a quantitative surrogate marker (0.0-1.0) of liver fibrosis (Metavir F0-F4), hepatic steatosis (0.0-1.0, S0-S3), and nonalcoholic steatohepatitis (NASH) (0.0-0.75, N0-N2). The absence of steatosis (S<0.41) precludes the diagnosis of NASH.

  

NASH FibroSure® Plus is recommended for patients with suspected nonalcoholic fatty liver disease. It is not recommended for patients with other liver diseases. It is also not recommended in patients with Gilbert disease, acute hemolysis, acute viral hepatitis, drug induced hepatitis, genetic liver disease, autoimmune hepatitis and/or extra- hepatic cholestasis. Any of these clinical situations may lead to inaccurate quantitative predictions of fibrosis.

This test was developed, and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

  

Patient should be fasting for at least eight hours.

  
Serum
  
  
3.5 mL
  
2.0 mL
  

Immediatley following collection, mix sample by inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
  4. Freeze
  
  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
  4. Freeze
  

Patient's age and gender

  

Frozen (preferred) - 7 days

Refrigerated - 72 hours

Ambient - 72 hours

  
  • Gross hemolysis
  • Gross lipemia
  • Improper labeling
  • Nonfasting specimen
  • Patient <14 years of age
  
LabCorp Burlington (550960): R-NX
  
4 - 6 days
  

An interpretive report will be provided

  
82172
82247
82465
82947
82977
83010
83883
84450
84460
84478
  
Yes
  
  
11/11/2016
  
04/19/2023
  
03/01/2022