Treponema pallidum by IHC

Alphabetical Test listing

Treponema pallidum by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
Treponema pallidum by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
Spirochete
  
  • All IHC stains will include a positive control tissue
  
  • T Pallidum is used to identify syphilis in tissue based material
  • This stain is an important adjunct in the identification of syphilis, since the organism is refractory to culture, and histochemical stains are difficult to interpret
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • T Pallidum identifies the causative agent of syphilis

 Staining pattern

  • Red, corkscrew bacterial pattern of staining (a red chromogen is used with this antibody)

 

 

 

 

 

 

 

 

References

  1. Guarner J et al: Congenital syphilis in a newborn: an immunopathologic study. Mod Pathol 1999; 12:82-87.
  2. Beckett JH et al: Immunoperoxidase localization of treponema pallidum: its use in formaldehyde-fixed and paraffin-embedded tissue sections. Arch Pathol Lab med 1979 Mar; 103(3): 135-8.
  
88342 - 1st stain
88341 - each additional stain
  
09/13/2017
  
10/17/2018
  
01/12/2024