Lavender (EDTA), 4mL tube(s)
Refrigerated - 48 hours
Specimens are required to be received at the performing laboratory by 4pm, Mo - Fri. No weekend processing.
Fluorescent flow cytometry
TNFRSF13C (BAFF-R) and TNFRSF13B (TACI) gene mutations have been described in a small subset of patients with humoral immunodeficiencies classified as CVID. The majority of TNFRSF13B mutations preserve TACI protein expression and require genetic testing to identify pathogenic or potentially pathogenic mutations/variants.