Hepatitis B Virus (HBV) Genotype
Hepatitis B Virus (HBV) Genotype-994
HBV Subtype
The HBV genotype assay classifies the virus present in the sample into one of nine recognized genotypes (A-I) via sequence analysis of the DNA polymerase gene. Disease progression and response to therapy may be influenced by genotype. In addition, the HBV genotype assay identifies and reports sequence polymorphisms in the basal core promotor (BCP) and coding regions of the HBV precore gene that result in either decreased levels, or complete absence, of HBeAg expression in chronically infected patients.
This assay may not be successful when the HBV viral load is <500 IU/mL.
Immediatley following collection, mix sample by inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Centrifuge within 6 hours of collection
- Aliquot serum into Labcorp transport vial
- Freeze
Immediatley following collection, mix sample by inverting 5 times
- Centrifuge within 6 hours of collection
- Aliquot plasma into Labcorp transport vial
- Freeze
Frozen (preferred) - 14 days
- Quantity not sufficient for analysis
- Heparin/SPS plasma (wrong anticoagulant)
- Gross hemolysis
- Specimen not frozen
Polymerase chain reaction (PCR) amplification and DNA sequencing
An interpretive report will be provided