Trofile®

Alphabetical Test listing

Trofile®-13573

  
TrofileĀ®
  
13573
  
LAB13573
  
TROFILE
  
CCR5
Chemokine co-receptor tropism
Co-Receptor Tropism (phenotypic)
CXCR4
HIV
Monogram Biosciences
Tropism
  
  • Detect HIV-1 co-receptor tropism
  • Determine eligibility for CCR5 antagonist therapy such as maraviroc (SelzentryTM)
  

This test should be used for patients with documented HIV-1 infection and viral loads ≥1000 copies/mL

  
EDTA plasma
  
  
3.0 mL
  
  • Collect specimen in two (2) Lavender (EDTA), 4mL tubes
  • Immediatley following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
  
  1. Spin 
  2. Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as EDTA plasma, within six (6) hours of sample collection
  3. Freeze within six hours of sample collection

 

  

Frozen (strict)

  
  • Insufficient volume (QNS)
  • Heparinized plasma
  • Non-frozen specimen
  
Monogram Biosciences (E3100) via LabCorp (553100): R-LC
  
35 days
  

Polymerase Chain Reaction (PCR) amplification and viral culture

  

An interpretive report will be provided

  
Result 51969-4
  
04/08/2019
  
04/13/2022
  
04/12/2022