Analysis of MSI at 5 gene loci.
MSI PCR is often performed in conjunction with analysis of DNA mismatch repair enzymes by immunohistochemistry. Deficient DNA repair and MSI are associated with Lynch Syndrome, and may also be used to determine eligibility for drug therapy
Along with the tumor specimen, a normal control from the patient must be submitted.
The preferred normal control is a negative tissue block. If none is available, 5.0 mL of whole blood (ACD, EDTA or NaCitrate) may be submitted.
Formalin-fixed, paraffin-embedded (FFPE) tissue block
Molecular Medicare billing request
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.
Ambient
Multi-plex Polymerase Chain Reaction (PCR) analyzed by capillary electrophoresis
An interpretative report will be included
Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.