Itraconazole

Alphabetical Test listing

Itraconazole-13478

  
Itraconazole
  
13478
  
LAB13478
  
ITR
  
Sporanox
  

Monitoring Itraconazole therapy.

Itraconazole is used in the treatment of susceptible fungal infections in immunocompromised and immunocompetent patients. It has been recommended that routine monitoring occur during the first week of therapy to ensure therapeutic levels are achieved for each individual and to continue monitoring if clinical presentations do not improve or decline.

  
Serum
  
  
1.0 mL
  
0.5 mL
  
  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a T ransfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  
EDTA plasma
  
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times to prevent clotting

  
  1. Spin within two (2) hours of sample collection
  2. Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as EDTA plasma
  

Transfer vial/tube with cap - 12mL (LabCorp)

  

Refrigerated (preferred) - 14 days

Ambient - 14 days

Frozen - 14 days

  
  • Gel barrier (SST) tube.
    • The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may be clinically significant.
  
LabCorp Burlington (700833): R-LC
  
Mo - Fr
  
3 - 6 days
  

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

  

An interpretive report will be provided

  
80189
  
Result 10989-2
  
04/09/2019
  
11/10/2021
  
12/31/2023