Monitoring Itraconazole therapy. Itraconazole is used in the treatment of susceptible fungal infections in immunocompromized and immunocompetent patients. It has been recommended that routine monitoring occur during the first week of therapy to ensure therapeutic levels are achieved for each individual and to continue monitoring if clinical presentations do not improve or decline.
Spin and separate
LabCorp 12mL plastic transport tube labelled as serum or plasma
Do not use a gel barrier (SST) tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may be clinically significant.
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
An interpretive report will be provided