Osmotic fragility, erythrocyte

Alphabetical Test listing

Osmotic fragility, erythrocyte-994

  
Osmotic fragility, erythrocyte
  
994
  
LAB994
  
MSO
  
FRAGILITY, OSMOTIC (RBC)
Osmotic Fragility
RBC Fragility, Erythrocytes
Red Cell Fragility
Spherocytic Hemolytic Disease
  
  • Functional testing of red blood cell sensitivity to osmotic stress
  • Do not use to distinguish between spherocytes in hereditary spherocytosis and acquired autoimmune hemolytic anemia
  
EDTA whole blood
  
  
5.0 mL
  
1.0 mL
  

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting.

  
  1. Draw Mon - Wed ONLY
  2. Refrigerate specimen within 30 minutes of collection

 

  

Lavender (EDTA), 4mL

  
Heparin whole blood
  

Dk green heparin (Li or Na), no gel

 

 

  

Immediately following collection, mix sample by inverting 5 - 10 times to prevent clotting.

  

Dk green heparin (Li or Na), no gel 

  

Refrigerated (strict) - 72 hours

Ambient - NO

Refrigerated - NO

Specimens must be received and testing performed by ARUP within 72 hours of collection.

  
  • Grossly hemolyzed blood
  • Specimens received room temperature or frozen
  
ARUP Laboratories Inc (2002257) via LabCorp (284205): R-2002257X
  
Mo - Fr
  
4 - 6 days
  

Spectrophotometry

  

Within normal curve limits

  

For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.

  
85555
  
Result 4667-2
  
05/24/2019
  
12/18/2023
  
12/18/2023