Nucleophosmin (NPM1) Mutation Analysis, Varies

Alphabetical Test listing

Nucleophosmin (NPM1) Mutation Analysis, Varies-994

  
Nucleophosmin (NPM1) Mutation Analysis, Varies
  
994
  
LAB994
  
MSO
  
NPM1
NPM1 MRD
Nucleophosmin Mutation Analysis
  

As a prognostic indicator in patients with newly diagnosed acute myelogenous leukemia with normal karyotype and no FLT3 variant and as a leukemia-specific marker of minimal residual disease

  
Whole blood
  
  
10 mL
  
8 mL
  

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting

  

Do not spin; Send specimen in original tube.

  

Lavender (EDTA), 4mL

or

Yellow ACD-B

  
Bone marrow
  
  
4 mL
  

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting

  

Do not spin; Send specimen in original tube.

  

Lavender (EDTA), 4 mL

Yellow ACD-B

  

Refrigerated (preferred) - 5 days

Ambeint - 72 hours

  
  • Gross hemolysis
  • Moderately to severely clotted
  • Bone marrow biopsies
  • Paraffin-embedded bone marrow clots
  • Slides
  • Paraffin shavings
  
Mayo Clinic Laboratories (NPM1Q); R-NX
  
Mo - Sa
  
10-14 days
  

RNA: Reverse-Transcription Quantitative PCR (RT-qPCR)

DNA: Polymerase Chain Reaction (PCR) with Fragment Analysis by Capillary Gel Electrophoresis

  

See report

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81310
  
03/04/2024
  
03/05/2024
  
03/04/2024