Angiotensin-converting enzyme

Alphabetical Test listing

Angiotensin-converting enzyme-13344

  
Angiotensin-converting enzyme
  
13344
  
LAB13344
  
ACE
  
ACE, serum
  

High in sarcoidosis, more often when the disease is active. Of value in assessing the response of sarcoidosis to corticosteroid therapy.

  

Stop administration of Captopril, Enalapril, or Lisinopril for 12 hours prior to sample collection (reduces ACE activity).

  
Serum
  
  
0.5 mL
  
0.2 mL
  

Immediatley following collection, mix sample by inverting 5 times

  
  1. Allow specimen to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow specimen to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp) labelled as "serum"
  
  

Ambient  (preferred) - 10 days

Refrigerated  - 10 days

Frozen - 7 months

Freeze/thaw cycles - stable x4

 

  
  • Captopril, enalapril, or lisinopril administration
  • Hemolyzed specimen
  • Icteric specimen
  • Whole blood
  • Cerebrospinal fluid (CSF)
  • EDTA plasma specimen received
  
LabCorp Burlington (010116): R-LC
  
Mo - Sa
  
5 days
  

Kinetic

  

0 - 2 years:   18 - 95 units/L
3 - 14 years: 22 - 108 units/L
≥ 15 years:   14 - 82 units/L

  

Changes in serum ACE correlate with clinical status and results of gallium scans (which reflect presence and activity of inflammatory granulomatous lesions). Falling ACE level is a favorable prognostic sign. Rising levels may reflect activity uncontrolled by therapy.

  
82164
  
Result 2742-5
  
03/27/2019
  
02/20/2024
  
02/20/2024