Isocitrate dehydrogenase 1 & 2 gene mutation assay

Alphabetical Test listing

Isocitrate dehydrogenase 1 & 2 gene mutation assay-Pathology add-on

  
Isocitrate dehydrogenase 1 & 2 gene mutation assay
  
Pathology add-on
  
R132
R172
IDH1
IDH2
Isocitrate dehydrogenase 1 - soluble
Isocitrate dehydrogenase 2 - mitochondrial
  

Detection of point mutations in codon 132 of the IDH1 gene and codon 172 of the IDH2 gene. Mutations in these genes are used to identify and stage brain tumors.

  
Surgical or biopsy tumor specimen
  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

Tissues should be processed according to standard FFPE protocols. Over fixing of samples should be avoided as this can cause DNA degradation.

 

  

Formalin-fixed, paraffin embedded (FFPE) tissue block.

  

Ambient

  
AHL - Molecular Diagnostics: D
  
Varies
  
8 days
  

Polymerase Chain Reaction (PCR) with Melt Curve analysis

  

An interpretative report will be provided

  
81403 - IDH 1
81403 - IDH 2
  
10/26/2010
  
07/27/2018
  
03/13/2020