Hemoglobinopathy fractionation cascade

Alphabetical Test listing

Hemoglobinopathy fractionation cascade-13520

  
Hemoglobinopathy fractionation cascade
  
13520
  
LAB13520
  
HGFRAC
  
Hemoglobin electrophoresis
  
  • Hgb F
  • Hgb A
  • Hgb A2
  • Hgb S

Reflex for Hgb Solubility includes:

  • Hgb C
  • Hgb E
  • Hgb Variant
  

Diagnose thalassemias and hemoglobin variants

  
EDTA whole blood
  
  
1.5 mL
  
0.8 mL
Submission of the minimum volume does not allow for repeat testing
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Lavender (EDTA), 4mL

  

State the patient's age, ethnic background, MCV, transfusion history, and any other known hematological data on the test request form.

  

Refrigerated (preferred) – 14 days

Ambient – 14 days

Frozen – 14 days

Freeze/thaw cycles - stable x3

  
  • Clotted specimen
  • Aged specimen
  • Improperly stored blood samples
  
LabCorp (121690): R-LC
  
Mo - Sa
  
2 - 5 days
  

Capillary electrophoresis (CE)

High-pressure liquid chromatography (HPLC)

Hgb Solubility: Sodium hydrosulfite reduction

  

% (see report for interpretation) 

  
83020

Additional CPT code(s), if appropriate:
85660 - Hgb solubility
or
83021 - Hgb fractionation by HPLC
or
83021 - Hgb fractionation by HPLC
85660 - Hgb solubility
  
03/01/2021
  
12/21/2023
  
12/21/2023