Carbamazepine & epoxide, free and total

Alphabetical Test listing

Carbamazepine & epoxide, free and total-2755

  
Carbamazepine & epoxide, free and total
  
2755
  
LAB2755
  
CFT
  
Carbatrol®
CBZ
Epitol®
Epoxide
Tegretol®
  
  • Carbamazepine
  • Carbamazepine-10,11-epoxide
  • Carbamazepine, unbound
  • Carbamazepine epoxide, unbound
  

Therapeutic drug management

  
Serum
  
  
5.0 mL
  
1.2 mL
  

Trough levels are most reproducible

  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Serum/plasma transfer vial/tube (MedTox), labelled as serum, within two (2) hours of sample collection
  
  
Heparin plasma
  

Dk green heparin (Li or Na), no gel - Two (2)

 

  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

  
  1. Spin
  2. Transfer plasma to a Serum/plasma transfer vial/tube (MedTox), labelled as the appropriate plasma type, within two (2) hours of sample collection
  

Refrigerated (preferred)

Ambient - 3 days

Frozen - OK

  

Gel barrier tubes

  
MedTox Laboratories (2153): R-MX
  
Daily
  
2 - 3 days
  

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

  

Carbamazepine, total: 4.0 - 12.0 µg/mL 
Carbamazepine, free:  0.6 - 4.2 µg/mL 


Carbamazepine - epoxide, total: 0.4 - 4.0 µg/mL 
Carbamazepine - epoxide, free:  0.2 - 2.0 µg/mL 

  
80161 - Carbamazepine epoxide
80156 - Carbamazepine total
80157 - Carbamazepine unbound
  
04/16/2015
  
07/12/2023
  
07/12/2023