Antiphosphatidylserine, IgA, IgG, IgM

Alphabetical Test listing

Antiphosphatidylserine, IgA, IgG, IgM-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Useful for:

An adjunct to β2-glycoprotein and anticardiolipins in diagnosing aPS (antiphospholipid syndrome) for assessing thrombotic risk and other obstetric complications such as miscarriage or fetal growth restriction.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot a minimum of 30 minutes
Spin within two (2) hours of sample collection

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube - 5 mL

Alternate processing instructions:

Allow sample to clost
Spin
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp) labelled as serum, within two (2) hours of sample collection

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Gross hemolysis
Bacterial contamination
Lipemia

Performing lab:

LabCorp Burlington (117994): R-NX

Days set up:

Tu, Th

TAT:

2 - 4 days

Method:

Enzyme-linked immunosorbent assay (ELISA)

Reference ranges:

IgM: 0 - 30 MPS
IgA: 0 - 19 APS
IgG: 0 - 30 GPS

Clinical information:

High serum levels of antiphospholipid antibodies are frequently detected in patients with autoimmune (ie, SLE) and nonautoimmune diseases, as well as in apparently healthy individuals. These antibodies have been associated with an increased risk for recurrent arterial and venous thrombotic events, thrombocytopenia, and fetal loss.

CPT codes:

86148 x 3

LOINC code:

Result 14246-3

Date created:

08/19/2019

Revised date:

07/11/2022

Review date:

07/11/2022