Hereditary hemochromatosis

Alphabetical Test listing

Hereditary hemochromatosis-5638

Test name:

Test number:

5638

Excellian order number:

LAB5638

Abbreviation:

Alternate names:

C282Y mutation
H63D mutation
HFE

Useful for:

Detection of two point mutations in the human HH gene; C to Y amino acid change at position 282 and H to D amino acid change at position 63. These mutations are associated with iron accumulation and subsequent damage to organs.

This is a genetic test and needs only to be performed once in a lifetime.

Specimen type:

EDTA whole blood

Collection container:

Lavender (EDTA), 4mL

Volume:

3.0 mL

Collection instructions:

Only one (1) tube needs to be drawn for any combination of the following tests:
- Calreticulin Exon 9 Assay
- Factor V Leiden Mutation
- Factor 2 Mutation
- Hereditary Hemochromatosis
- JAK2 V617F Mutation Detection
- MTHFR C677T assay
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

Questions? Call the Molecular Diagnostics Lab at (612) 863-4475.

Transport container:

Lavender (EDTA), 4mL

Alternate specimen type:

ACD whole blood
Sodium citrate (Na Cit) whole blood

Alternate collection container:

Lt blue Sodium citrate (Na Cit) - 2.7mL

Yellow ACD (A or B)

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

Alternate transport container:

Lt blue Sodium citrate (NaCit)

Yellow ACD (A or B)

Required forms/information:

Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
All information requested is required in order for your request to be completed

Transport and stability:

Ambient (preferred)

Refrigerated - OK

Reason for rejection:

Improper label (unlabeled or mislabeled)
Wrong container (anticoagulant or solution)
Improper blood/anticoagulant ratio
Delay in transport
Improper storage
Inappropriate timing of collection
Interfering substances

Performing lab:

AHL - Molecular Diagnostics: D

Days set up:

Varies

TAT:

7 days

Method:

PCR & RFLP analysis by gel electrophoresis

Reference ranges:

Homozygous normal

Preauthorization:

This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.

CPT codes:

81256

Subject to medical necessity (Y/N):

Yes

Other billing information:

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
All information requested is required in order for your request to be completed

Molecular Medicare billing request

Date created:

11/30/2001

Revised date:

07/30/2018

Review date:

01/15/2024