All IHC stains will include a positive control tissue

• Glycophorin A is useful in the identification of erythroleukemia, and to establish the lineage of the blast cells in acute leukemia
• This antibody can be used on fixed smears or on paraffin-embedded tissue

Submit a formalin-fixed, paraffin-embedded tissue

Formalin-fixed, paraffin-embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• Glycophorin A is an antibody directed against a molecule found in erythroid cells
• Glycophorin A is present in all stages of differentiation of a RBC, from an erythroblast to a mature erythrocyte

 Staining pattern

• Granular cytoplasmic

References

1. Greaves MR et al: Monoclonal anti-glycophorin as a probe for erythroleukemia. Blood, 1983;61:645-51.
2. Erber WN et al: A new monoclonal antibody that detects glycophorin A for the diagnosis of erythroleukemia. Hematol Rev 1991;5:113-20.