TP53 mutation-994

Test info

  
TP53 mutation
  
994
  
LAB994
  
MSO
  
P53
CLL
BCLL
TP53 gene somatic mutation analysis
  

Evaluating chronic lymphocytic leukemia patients at diagnosis or during disease course for the presence of TP53 gene variants indicating high risk of disease progression and adverse outcomes.

This test is not intended for the evaluation of patients suspected of having an inherited or germline TP53 cancer syndrome (eg, Li Fraumeni syndrome)

Specimen

  
EDTA whole blood
  

  
3 mL
  
1 mL
  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

  

Send whole blood specimen in original tube. Do not aliquot.

  

Molecular Hematopathology Patient Information

Molecular Medicare Billing Request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

  

Refrigerated (preferred) - 10 days

Ambient - 10 days

  
2 weeks
  
  • Gross hemolysis
  • Extracted DNA
  • Moderately to severely clotted

Performance

  
Mayo Clinic Laboratories (P53CA): R-NX
  
Mo - Fr
  
8 -14 days
  

Polymerase Chain Reaction (PCR) and Sanger Sequencing

 

Clinical and Interpretive info

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81352
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Molecular Medicare Billing Request

Tracking

  
03/13/2023
  
05/23/2024
  
03/14/2023