Alpha-Synuclein Protein Aggregates, Spinal Fluid-994

Test info

  
Alpha-Synuclein Protein Aggregates, Spinal Fluid
  
994
  
LAB994
  
MSO
  
SAAmplify-aSYN
SYNTap
Amprion
Alpha-Synuclein Aggregates
Parkinson Disease (PD)
Dementia with Lewy bodies (DLB)
Lewy body disease (LBDCSF)
Alzheimer disease (AD)
Mild cognitive impairment (MCI)
Multiple system atrophy (MSA)
RT-QuIC
Seed Amplification Assay (SAA)
Synucleinopathy
AMP1200
  

Detection of pathogenic alpha-synuclein (alpha-synuclein aggregates) in adult patients being assessed for clinically uncertain cognitive decline or clinically uncertain parkinsonian syndromes

Specimen

  
Cerebrospinal fluid (CSF)
  

Screw-capped polypropylene vial/tube, sterile (Mayo)

  
1.0 mL
  
0.3 mL
  
  1. Perform lumbar puncture and discard the first 1 to 2 mL of cerebrospinal fluid (CSF).
  2. Collect CSF directly into a sterile polypropylene tube.
  3. Freeze sample upright 
  
  1. Inspect specimen for visible discoloration.Specimen must be clear and colorless to perform testing.
  2. Do not centrifuge
  

Screw-capped polypropylene vial/tube, sterile (Mayo)

  

Frozen (preferred) - 60 days

Refrigerated - 14 days

  
  • Hemolysis
  • Icterus
  • Unclear/discolored specimen
  • Specimens not collected in polypropylene collection tubes

Performance

  
Amprion Inc via Mayo Clinic Laboratories (ASYNC)
  
Varies
  
15 - 18 days
  

Seed Amplification Assay (SAA)

Clinical and Interpretive info

  

An interpretive report will be provided

  
Results must be interpreted in conjunction with other patient clinical information.

Billing

  
0393U

Tracking

  
05/05/2025
  
05/05/2025