Varicella zoster virus (VZV) antibodies, IgM-13374
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Test info
VZV IgM
Detect IgM antibodies specific for VZV. These IgM antibodies, if present, can help confirm a diagnosis of VZV acute infection. The IgM response to VZV can be detected at seven days postinfection and usually peaks at 14 days. If a patient presents more than nine days after the appearance of a rash, this assay should not be used.
Specimen
Immediately following collection, thoroughly mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
- Hemolysis
- Lipemia
- Gross bacterial contamination
- Plasma samples
Performance
Enzyme immunoassay (EIA)
Clinical and Interpretive info
Negative: <0.91 index
Borderline: 0.91−1.09 index
Positive: >1.09 index