13q14 deletion by FISH-4280G (bone marrow) or 4280H (blood)

Test info

  
13q14 deletion by FISH
  
4280G (bone marrow) or 4280H (blood)
  
LAB4280G - CYTOGENETIC BONE MARROW STUDIES
LAB4280H - CYTOGENETIC LEUKEMIC BLOOD STUDIES
  
Deletion 13q14
  
Chronic Lymphocytic Leukemia
CLL
CLL Full Panel
CLL Prognostic Panel
FISH
Fluorescence in Situ Hybridization
SLL
Small Lymphocytic lymphoma
13q deletion
13q14
  

Deletion 13q14 is a recurring abnormality of Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic lymphoma (SLL) and useful as a cytogenetic prognostic indicator. 

This test can be ordered individually or as either part of a CLL full panel or CLL prognostic panel. See the individual panel tests for more details.

Specimen

  
Bone Marrow aspirate
  

Bone marrow aspirate:

Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube

  

- or -

  1. Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
  2. Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

  
5 mL
  
3 mL
  

Transfer aspirate from syringe to transport container. 

  

Submit entire specimen unspun.

  

Sterile vial/tube

  

or

Dk green Sodium heparin (Na hep), no gel

  
Bone Marrow Core
Whole blood
Touch Prep Slides
  

Bone Marrow Core:

Submit in sterile tube/cup filled with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline

or 

Whole blood:

Dk green Sodium heparin (Na hep), no gel

  
Bone Marrow core: 10 mm
Whole blood: 4 mL
  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting.

  

Submit entire specimen unspun

  
  

AHL Cytogenetics Oncology Request

  

Ambient

  
Specimens retained until completion of all testing
  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Delay in transport
  • Improper storage
  • Leaking container
  • Slides broken beyond repair

Performance

  
AHL - Cytogenetics: X
  
Mo - Fr
  
7 business days
  

Fluorescence in situ hybridization (FISH)

Clinical and Interpretive info

  

Normal or Abnormal with interpretation.

 

Billing

  
88271 x 3
88275
88291
  
Yes
  

Tracking

  
03/18/2021
  
02/24/2026
  
02/20/2026