• All IHC stains will include a positive control tissue

• In normal cells, NF labels neurons, neuronal processes, peripheral nerves, sympathetic ganglion cells, adrenal medulla, and neuroendocrine cells
• Tumors that react with NF include neuroblastomas, ganglioneuromas, pheochromocytomas, paragangliomas, chemodectomas, neuroendocrine tumors, carcinoid tumors, and some Merkel cell tumors

Submit a formalin-fixed, paraffin embedded tissue block

Formalin-fixed, paraffin embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• Recognizes polypeptide subunits that are present in the intermediate filament NF
• NF expression is limited to neuronal cells

Staining pattern

• Cytoplasmic based staining