Detecting and identifying pathogenic organisms including bacteria, fungi, DNA viruses, RNA viruses, and parasites in cerebrospinal fluid

Sterile vial/container

1. Masks should be worn by those collecting and processing specimens for this assay.
2. Handle all vials under sterile technique when open to the air.
3. A separate collection vial of CSF is preferred.
4. Submit specimen from collection vial 2, 3, or 4, as specimens from vial 1 are not acceptable.
5. Indicate on the label which vial is being submitted.

Screw-capped polypropylene vial/tube, sterile (Mayo)

Frozen (preferred) - 21 days

Refrigerated - 7 days

• Gross hemolysis
• Shunt fluid
• Ventricular fluid
• Heat-inactivated specimen
• CSF collection tube 1

Metagenomic Next-Generation Sequencing (NGS)

Negative

No pathogenic DNA virus detected

No pathogenic RNA virus detected

No pathogenic parasite detected

No pathogenic bacterium detected

No pathogenic fungus detected