• All IHC stains will include a positive control tissue

• B72.3 reacts with a wide variety of adenocarcinomas, including ovarian, endocervix, endometrium, distal esophagus, stomach, colon, lung, breast, prostate, pancreas, and bile ducts
• B72.3 does not react with hepatocellular carcinomas (0/20 cases)
• Use B72.3 with panel in differentiating between malignant mesothelioma versus adenocarcinoma (see section on immunohistochemistry panels)

Submit a formalin-fixed, paraffin embedded tissue block

Formalin-fixed, paraffin embedded (FFPE) tissue block

Tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• Reacts with a high molecular weight glycoprotein designated tumor-associated glycoprotein-72 (TAG-72)

 Staining patterns

• Cytoplasmic and/or membrane/luminal staining

References

1. Long et. al.: Reactivity of B72.3 with Adenocarcinomas an Immunohistochemical Study of 476 cases, Cancer 72:2495-8, 1993.