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CMV Resistance: Ganciclovir, Foscarnet, Cidofovir, Maribavir, and Letermovir-994

Test info

Test name:

CMV Resistance: Ganciclovir, Foscarnet, Cidofovir, Maribavir, and Letermovir

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

CMV drug resistance
CMV resistance
Cytomegalovirus (CMV) genotype
Cytomegalovirus antiviral drug resistance
CMV drug resistance by NGS
UL54
UL97

Tests included:

Ganciclovir UL97
Cidofovir UL54
Foscarnet UL54
Ganciclovir UL54
Maribavir UL27
Letermovir UL56

Useful for:

Provides antiviral susceptibility information for ganciclovir, foscarnet, cidofovir, maribavir, and letermovir. Intended for patients with viral load >2.6 log IU/mL.

Specimen

Specimen type:

EDTA plasma

Collection container:

Lavender (EDTA), 4mL

Volume:

3.0 mL

Minimum volume:

2.5 mL

Collection instructions:

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

Processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Screw cap transfer vial/tube (Mayo T914), labelled as EDTA plasma
Freeze

Transport container:

Screw cap transfer vial/tube (Mayo T914)

Required forms/information:

If available, please submit the following: most recent viral load and test date; information on current or past drug therapy.

Transport and stability:

Frozen (preferred) - 1 month

Ambient - 8 hours

Refrigerated - 3 days

Reason for rejection:

Heparinized specimens
Serum specimens
Frozen whole blood

Performance

Performing lab:

ARUP (3004615) via Mayo Clinic Laboratories (ZW242): R-NX

Days set up:

Daily

TAT:

4 - 10 days

Method:

Massively Parallel Sequencing

Clinical and Interpretive info

Reference ranges:

An interpretive report will be provided

Billing

CPT codes:

87910
87900

Tracking

Date created:

01/02/2024

Revised date:

09/30/2025

Review date:

09/30/2025