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5-HIAA, plasma-994

Test info

Test name:

5-HIAA, plasma

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

5HIAA
5-hydroxyindoleacetic acid

Useful for:

Plasma 5-hydroxy-indoleacetic acid (5HIAA or 5-HIAA) is a metabolite of serotonin that can be elevated as a result of carcinoid tumors/carcinoid syndrome.

Specimen

Patient preparation information:

Patient should avoid consumption of bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for a 72-hour period prior to and during collection.

Specimen type:

Heparin plasma

Collection container:

Dk green heparin (Li or Na), no gel

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, mix sample by inverting 8 - 10 times to prevent clotting

Processing instructions:

Spin within 45 minutes of sample collection
Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as the appropriate Heparin plasma type
Freeze

Transport container:

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Alternate specimen type:

EDTA plasma

Alternate collection container:

Lavender (EDTA), 4mL

Alternate processing instructions:

Spin within 45 minutes of sample collection
Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp) labelled as EDTA plasma
Freeze

Transport and stability:

Frozen (preferred) - 14 days

Freeze/thaw cycles - stable x 6

Ambient - 3 days

Refrigerated - 3 days

Reason for rejection:

Gross hemolysis

Performance

Performing lab:

Esoterix Endocrinology via LabCorp (504510): R-NX

Days set up:

TAT:

16 days

Method:

High-pressure liquid chromatography (HPLC)/tandem mass spectrometry

Clinical and Interpretive info

Reference ranges:

<22 ng/mL

Billing

CPT codes:

83497

LOINC code:

Result 1693-1

Tracking

Date created:

06/26/2019

Revised date:

10/20/2023

Review date:

10/20/2023