All IHC stains will include a positive control tissue

• CD30 can identify RS and mononuclear cells in classic Hodgkin's Disease (see section on immunohistochemistry panels), most anaplastic large cell lymphomas, and lymphomatoid papulosis
• CD30 can also identify some plasma cells
• CD30 reactivity can also be seen in some peripheral T cell NHL and some B-cell immunoblastic NHL
• CD30 staining can be seen in embryonal carcinomas and occasional pancreatic acinar carcinomas

Submit a formalin-fixed, paraffin-embedded tissue

Formalin-fixed, paraffin-embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• Ber-H2 reacts with a glycoprotein often found in RS cells and anaplastic large cell lymphomas

Staining pattern

• Cell surface membrane often with Golgi pattern