CA 15-3-3551

Test info

  
CA 15-3
  
3551
  
86300.1
  
Ca 15-3
  
C15
Cancer antigen 15-3
Cancer antigen, breast
  

Cancer antigen 15-3 (CA 15-3) is used to monitor response to breast cancer treatment and disease recurrence.

The test method changed on 1/3/2023. If this test has been used for serial monitoring, rebaselining is recommended. Rebaselining consists of 2 measurements, collected 3-6 weeks apart.
The Roche Elecsys CEA assay is an electrochemiluminescence immunoassay "ECLIA" performed on the Roche Cobas "e" immunoassy analyzers.
Values obtained with different assay methods may be different and cannot be used interchangeably.

  

Biotin supplements may cause clinically significant interference for this test assay. If interference is suspected, it is strongly recomended that biotin is discontinued for at least one week prior to retesting

Specimen

  
Serum
  
  
1.0 mL
  
0.5 mL
  

Immediately following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
Serum
Lithium heparin (Li hep) plasma
  
  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times 

  

Red:

  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a False bottom plasma/serum transport vial/tube (AHL), labelled as serum, within two (2) hours of sample collection

Lt green:

  1. Spin within two (2) hours of sample collection
  

Lt green plasma separator (PST)

False bottom plasma/serum transport vial/tube (AHL)

  

Refrigerated (preferred) - 5 days

Ambient - 2 days

Frozen - 90 days

  
  • Improper labels (unlabeled or mislabeled)
  • Hemolysis (some procedures)
  • Improper anticoagulant or ratio
  • Delay in transport
  • Improper storage temperature affecting results
  • Improper container
  • Leaking container resulting in compromised specimen
  • Quantity not sufficient (QNS)

Performance

  
AHL - Chemistry: C
  
Mo - Sa
  
1 - 3 days
  

Electrochemiluminescence immunoassay (ECLIA)

Clinical and Interpretive info

  

< 26.0 U/mL

Billing

  
86300
  
Yes
  

Tracking

  
11/28/2007
  
05/23/2024
  
11/09/2021