• Evaluating patients suspected of having Wegener granulomatosis (WG)
• Distinguishing between WG and other forms of vasculitis, in conjunction with MPO/Myeloperoxidase Antibodies, IgG, serum and ANCA/ Cytoplasmic Neutrophil Antibodies, serum (may be obtained as VASC/ Antineutrophil cytoplasmic antibodies vasculitis panel, serum)
• May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies

Gold serum separator (SST) tube

Immediately following collection, thoroughly mix sample by gently inverting 5 times

1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection

Gold serum separator (SST) tube

Red serum vial/tube - 5 mL

1. Allow sample to clot
2. Spin
3. Transfer serum to a False bottom plasma/serum transport vial/tube (AHL), labelled as serum, within two (2) hours of sample collection

False bottom plasma/serum transport vial/tube (AHL)

Refrigerated (preferred) - 7 days

Frozen - 21 days

• Improper labels (unlabeled or mislabeled)
• Hemolysis (some procedures)
• Plasma
• Delay in transport
• Improper storage temperature affecting results
• Improper container
• Leaking container resulting in compromised specimen
• Quantity not sufficient (QNS)

Chemiluminescent

< 20 CU   Negative
≥ 20 CU   Positive