Screening for genetic abnormalities:

• Trisomy 21 (Down syndrome)
• Trisomy 18 (Edwards syndrome)
• Trisomy 13 (Patau syndrome)
• Triploidy
• Monosomy X (Turner syndrome)
• Sex chromosome trisomies
• Microdeletions, including 22q11.2 deletion syndrome (optional)

Patient must be at least 9 weeks gestation

Tubes contained in the Natera test kit

1. Collect whole blood in two (2) Cell Free DNA Streck tubes contained in the Natera collection kit
2. Draw with 21 gauge straight needle, NOT butterfly.
3. Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

• Allina Health facilities should order Prenatal DNA Sendout (LAB12637) which has been approved by the Test Formulary Committee and the OB/Gyn Service Line.
• Sites other than Allina Health: Due to the requirement for patient informed consent, the need for special request forms, and the potential for degradation of DNA in the specimens if transport is delayed, these specimens must be sent directly from the collecting site to the performing laboratory. Contact Natera to establish an account and obtain specimen collection and shipping kits.

Cell Free DNA Streck tubes in a Natera collection/shipping kit

Ambient (strict)

Refrigerated - NO

Frozen - NO

Cell Free DNA Analysis

An interpretive report will be provided