7AlphaC4 (7 alpha-hydroxy-4-cholesten-3-one)-994
Test info
7AlphaC4 (7 alpha-hydroxy-4-cholesten-3-one)
994
LAB994
MSO
7AC4
7C4
Bile Acid Diarrhea (BAD) marker
Bile Acid Malabsorption (BAM) marker
Bile Acid precursor or intermediate
Bile Acid Synthesis surrogate
7C4
Bile Acid Diarrhea (BAD) marker
Bile Acid Malabsorption (BAM) marker
Bile Acid precursor or intermediate
Bile Acid Synthesis surrogate
Serum 7AlphaC4 is a surrogate measure of stool bile acids (BA) and elevated levels may be diagnostic for bile acid malabsorption (BAM), also known as bile acid diarrhea (BAD)
Please note that this 7AlphaC4 test is for Bile Acid Malabsorption/Diarrhea. For cholestasis of pregnancy, Bile Acids, Fractionated and Total, LC/MS-MS [503640] is a different test.
Specimen
Sample collection in the morning after overnight fast is recommended.
Serum
0.5 mL
0.4 mL
Immediately following collection, mix sample thoroughly by gently inverting 5 times
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
- Freeze
EDTA plasma; Heparin plasma
Frozen (preferred) - 9 days
Freeze/thaw cycle - stable x6
Refrigerated - 9 days
Ambient - 1 day
Incorrect sample type
Performance
LabCorp (520550); R-NX
10 days
Tandem Mass Spectrometry (LC-MS/MS)
Clinical and Interpretive info
1.8 - 57 ng/mL
Billing
82542
Tracking
04/12/2024
04/12/2024