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IGH by FISH-4280J (malignant tissue)

Test info

Test name:

IGH by FISH

Test number:

4280J (malignant tissue)

Excellian order number:

LAB4280J - CYTOGENETICS MALIGNANT TISSUE STUDIES

Abbreviation:

IGH

Alternate names:

IGH rearrangement
Myeloma
Lymphoma
14q32.3 rearrangement

Useful for:

IGH rearrangements are common in a wide variety of hematologic disorders, including lymphoma and plasma cell dyscrasias.

Specimen

Specimen type:

Lymph Node (fresh tissue)

Collection container:

Sterile cup or tube

Volume:

5 mm3 tissue
5 mL

Collection instructions:

Place specimen in a sterile cup/tube with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

Processing instructions:

Submit entire fresh specimen.

Transport container:

Sterile specimen cup/tube

Alternate specimen type:

Paraffin embedded tissue
Slides
Touch prep slides

Alternate collection container:

Paraffin block

Three 4-micron cut slides and one H&E stained slide

Touch prep slides

Note: Heavy metal fixatives are unacceptable

Required forms/information:

AHL Cytogenetics Oncology Request

Transport and stability:

Ambient

Specimen retention time:

Slides - 6 months
Blocks will be returned post reporting

Reason for rejection:

Improper label (unlabeled or mislabeled)
Slides broken beyond repair
Heavy metal fixatives are unacceptable

Performance

Performing lab:

AHL - Cytogenetics: X

Days set up:

Mo-Fr

TAT:

14 business days

Method:

Fluorescence in situ hybridization (FISH)

Clinical and Interpretive info

Reference ranges:

Normal or Abnormal with interpretation

Billing

CPT codes:

Paraffin:
88366 x 2
Fresh Tissue/Touch Prep
88271 x 2
88275
88291

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Tracking

Date created:

09/13/2022