Antigliadin antibodies, IgG-13410
Test info
Deamidated gliadin antibodies, IgG
Deaminated gliadin antibodies, IgG
DGP, IgG
Detection of gliadin antibodies aids in the diagnosis and monitoring of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis
Specimen
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x 3
- Hemolysis
- Lipemia
- Gross bacterial contamination
Performance
Enzyme immunoassay (EIA)
Clinical and Interpretive info
Negative: 0-19
Weak Positive: 20-30
Moderate to Strong Positive: >30
A negative IgA result in an untreated patient does not rule out gluten-sensitive enteropathies, especially when associated with IgG gliadin antibodies. This can be explained by selective IgA deficiency, a relatively frequent finding in celiac disease. False-positives are possible as other gastrointestinal disorders are known to induce circulating antigliadin antibody, mainly Crohn disease, food protein intolerance, and postinfection malabsorption.