• Diagnosis of inflammatory demyelinating diseases (IDD) with similar phenotype to neuromyelitis optica (NMO) spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis
• Diagnosis of autoimmune myelin oligodendrocyte glycoprotein (MOG)-opathy
• Diagnosis of NMO
• Distinguishing NMOSD, acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis from multiple sclerosis early in the course of disease
• Diagnosis of ADEM
• Prediction of a relapsing disease course

For optimal antibody detection, recommend blood collection to occur before initiation of immunosuppressant medication.

Gold serum separator (SST) tube

Immediately following collection, mix sample by gently inverting 5 times

1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection

Gold serum separator (SST) tube

Red serum vial/tube, 5 mL

1. Allow sample to clot
2. Spin within two (2) hours of sample collection
3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum

Screw cap transfer vial/tube (Mayo T914)

Refrigerated (preferred) - 28 days

Frozen - 28 days

Ambient - 72 hours

• Gross hemolysis
• Gross lipemia
• Gross icterus

Flow Cytometry

Negative