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Powassan Virus, RNA, Molecular Detection, PCR, Spinal Fluid-994

Test info

Test name:

Powassan Virus, RNA, Molecular Detection, PCR, Spinal Fluid

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Powassan
Powassan virus
Powassan Virus, PCR, CSF
POWVC

Useful for:

Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using cerebrospinal fluid specimens
An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset)
This assay should not be used for screening asymptomatic individuals and should only be used to test patients with signs and symptoms of Powassan virus disease.

Limitations:

The Powassan virus polymerase chain reaction result may remain positive for a longer time in urine than in blood, serum, and cerebrospinal fluid (7 days or more).

Specimen

Specimen type:

Cerebrospinal fluid (CSF)

Collection container:

Sterile vial/container

Volume:

1 mL

Minimum volume:

0.3 mL

Collection instructions:

Send specimen from collection vial 2.
Do not centrifuge or heat inactivate.

Transport container:

Sterile vial

Transport and stability:

Refrigerated (preferred) - 7 days

Frozen - 7 days

Reason for rejection:

Heat-inactivated specimen

Performance

Performing lab:

Mayo Clinic Laboratories (POWVC); R-NX

Days set up:

Mo - Fr

TAT:

1- 5 days

Method:

Real-Time Polymerase Chain Reaction (PCR)

Clinical and Interpretive info

Reference ranges:

Negative

Clinical information:

Acute Tickborne Disease Testing Algorithm

Meningitis/Encephalitis Panel Algorithm

Billing

CPT codes:

87798

Tracking

Date created:

11/06/2023

Review date:

11/06/2023