B cell gene rearrangement-5453

Test info

  
B cell gene rearrangement
  
5453
  
LAB5453
  
GR
  
IgH Rearrangement
  

Detection of clonal rearrangements of immunoglobulin heavy chain genes that are associated with malignant processes.

Specimen

  
EDTA whole blood
  
  
4.0 mL
  
2.0 mL
  

Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting

  

Lavender (EDTA), 4mL,

 

  
4.0mL ACD whole blood
4.0mL Na Citrate whole blood
5.0cc bone marrow in EDTA
200mg FFPE tissue (B3/B5 not recommended)
  

Yellow ACD (A or B)

 

 Lt blue Sodium citrate (Na Cit) - 2.7mL 

 

Bone Marrow

Lavender (EDTA), 4mL

  
Whole blood 4.0mL (minimum 1.0 mL)
Bone marrow 5.0cc (minimum 1.0cc)
Tissue 200mg
  

Whole blood/bone marrow

  • Submit entire specimen

Tissue

  • Frozen preferred if not tested immediately
  • Freeze as quickly as possible at -20 to -70°C
  • Fresh tissues may be submitted in RPMI
  • Best results when used within 3 days
  • Recommended for tissues with high probability of immediate or pending orders
  • Formalin fixed tissue in a paraffin block (B3 and B5 fixatives are not recommended)

Questions call (612) 863-4475

  

Yellow ACD (A or B)

Lt blue Sodium citrate (NaCit)

Tissue

RPMI with Hepes/Pen strep/FBS -15 mL

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

  

Whole blood or bone marrow

Refrigerated (preferred) 

Ambient (OK)

Tissue

Ambient

  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Improper blood/anticoagulant ratio
  • Delay in transport
  • Improper storage
  • Inappropriate timing of collection
  • Interfering substances
  • Leaking container
  • Slides broken beyond repair

Performance

  
AHL - Molecular Diagnostics: D
  
Varies
  
8 days
  

PCR and Capillary electrophoresis

Clinical and Interpretive info

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81261
  
Yes
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Molecular Medicare billing request

Tracking

  
06/22/2006
  
05/15/2024
  
01/15/2024