Y chromosome microdeletion-994

Test info

  
Y chromosome microdeletion
  
994
  
LAB994
  
MSO
  

Five common Y chromosome microdeletions:

  • AZFa
  • AZFb
  • AZFc
  • AZFbc
  • AZFabc
  
  • Aids in determining the cause of azoospermia or oligospermia
  • Helps predict effectiveness of assisted reproductive technologies in men with Y chromosome microdeletions

Specimen

  
EDTA whole blood
  
  
2.0 mL
  
1.0 mL
  

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting

  

Submit tube unspun

  

Lavender (EDTA), 4mL

  
ACD whole blood
  

Yellow ACD (A or B)

 

  

Yellow ACD (A or B)

  

Molecular Medicare Billing Request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

  

Refrigerated (preferred) – 1 month

Ambient – 1 week

Frozen - NO

Performance

  
ARUP (2001778) via LabCorp (009985): R-NX
  
Varies
  
8 - 10 days
  

Polymerase Chain Reaction/Electrophoresis

Clinical and Interpretive info

  

See report

  

Y chromosome microdeletions are typically characterized by azoospermia, severe to moderate oligospermia, or abnormal sperm morphology/motility in men with a normal physical evaluation. Assisted reproductive techniques are contraindicated for men carrying AZFa, AZFb, AZFbc or AZFabc microdeletions, which are classically associated with spermatogenic failure.

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81403
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Molecular Medicare Billing Request

Tracking

  
10/12/2020
  
05/23/2024
  
12/18/2023