BCL2/IGH rearrangements are associated with Follicular lymphoma and can help differentiate diffuse Large B-cell lymphoma from High-grade lymphoma.

This test can be ordered individually or as part of a High Grade B-cell Lymphoma FISH Panel. See the panel test for details.

Bone marrow aspirate:

Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube

- or -

1. Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
2. Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

Transfer aspirate from syringe to transport container. 

Submit entire specimen unspun.

Sterile vial/tube

or

Dk green Sodium heparin (Na hep), no gel

Core submitted in sterile tube filled with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

Submit entire specimen.

Sterile tube/cup

AHL Cytogenetics Oncology Request

Ambient

• Improper label (unlabeled or mislabeled)
• Wrong container (anticoagulant or solution)
• Delay in transport
• Improper storage
• Leaking container
• Slides broken beyond repair

Fluorescence in situ hybridization (FISH)

Normal or Abnormal with interpretation

Medical necessity