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Glypican-3 by IHC-12376 - Technical only, 12379 - Technical & Interpretation

Test info

Test name:

Glypican-3 by IHC

Test number:

12376 - Technical only, 12379 - Technical & Interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

GPC3

Tests included:

All IHC stains will include a positive control tissue

Specimen

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin-embedded tissue

Transport container:

Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternate transport container:

Tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performance

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Clinical and Interpretive info

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

Glypicans are heparan sulfate proteoglycans (HSPGs) that are linked to the cell membrane by a glycosyl phosphatidylinositol (GPI) anchor
GPC3 is upregulated at mRNA and protein level in hepatocellular CA
Appears to be oncofetal (in fetal but not adult normal livers)

Staining pattern

Granular cytoplasmic and membranous staining

Billing

CPT codes:

88342 - 1st stain
88341 - each additional stain

Tracking

Date created:

07/03/2017

Revised date:

10/18/2018

Review date:

01/12/2024