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MYC/IGH/CEP8 FISH [malignant tissue]-4280J (malignant tissue)

Test info

Test name:

MYC/IGH/CEP8 FISH [malignant tissue]

Test number:

4280J (malignant tissue)

Excellian order number:

LAB4280J - CYTOGENETICS MALIGNANT TISSUE STUDIES

Abbreviation:

MYC/IGH/CEP8

Alternate names:

MYC
MYC/IGH
IGH
Diffuse large B-cell lymphoma
FISH
Fluorescence in situ hybridization
High grade B-cell lymphoma
t(8;14)
8q24
8q24 rearrangement
14q32

Useful for:

To identify patients with MYC rearrangements. Aids in differentiating diffuse large B-cell lymphoma from high-grade lymphoma.

This test can be ordered individually or as part of a High Grade B-cell Lymphoma FISH Panel. See the panel test for details.

Specimen

Specimen type:

Solid tumor or aspirate
Lymph Node (fresh tissue)

Collection container:

Sterile cup or tube

Volume:

5 mm3 tissue
5 mL

Collection instructions:

Place specimen in a sterile cup/tube with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

Processing instructions:

Submit entire fresh specimen.

Transport container:

Sterile specimen cup/tube

Alternate specimen type:

Touch prep slides

Required forms/information:

AHL Cytogenetics Oncology Request

Transport and stability:

Ambient

Specimen retention time:

Slides - 6 months
Blocks will be returned post reporting

Reason for rejection:

Improper label (unlabeled or mislabeled)
Slides broken beyond repair
Heavy metal fixatives are unacceptable

Performance

Performing lab:

AHL - Cytogenetics: X

Days set up:

Mo - Fr

TAT:

5 business days

Method:

Fluorescence in situ hybridization (FISH)

Clinical and Interpretive info

Reference ranges:

Normal or Abnormal with interpretation

Billing

CPT codes:

Paraffin:
88366 x 3
Fresh Tissue/Touch Prep:
88271 x 3
88275
88291

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Tracking

Date created:

09/12/2022

Review date:

09/12/2022