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Orexin-A/Hypocretin-1, Spinal Fluid-994

Test info

Test name:

Orexin-A/Hypocretin-1, Spinal Fluid

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Hypocretin
Orexin
Hypocretin-1
Orexin-A

Useful for:

Aiding in the diagnosis and differentiation of type 1 narcolepsy from other causes of hypersomnolence

Specimen

Patient preparation information:

Patient should not have recently received radioisotopes, either therapeutically or diagnostically, due to potential assay interference.

Specimen type:

Cerebrospinal fluid (CSF)

Collection container:

Sterile vial/container

Volume:

1.5 mL

Minimum volume:

0.5 mL

Processing instructions:

Obtain aliquot from second collection vial (preferred, not required)
Specimens should be centrifuged to remove any red cells prior to shipping

Transport container:

Screw-capped polypropylene vial/tube, sterile (Mayo)

Transport and stability:

Frozen (preferred) - 120 days

Refrigerated - 7 days

Ambient - 72 hours

Reason for rejection:

Gross hemolysis

Performance

Performing lab:

Mayo Medical Laboratories (ORXNA); R-NX

Days set up:

Twice monthly (Second and fourth Monday)

TAT:

3 - 32 days

Method:

Radioimmunoassay (RIA)

Clinical and Interpretive info

Reference ranges:

Normal: >200 pg/mL

Billing

CPT codes:

83519

Tracking

Date created:

03/04/2026

Review date:

03/04/2026