Certolizumab and anti-Certolizumab antibody-15273
Test info
Anti-TNF drug
Biologic drug level and anti-drug antibody
Biologic monitoring
Cimzia
Immunogenicity testing
TDM
TNF inhibitor
Provides certolizumab drug concentration and anti-certolizumab antibodies in order to optimize treatment and facilitate clinical decision-making. This assay may be helpful in any patient on certolizumab therapy for Crohn's disease, psoriasis, or other autoimmune condition.
Specimen
High serum biotin concentrations in patients taking biotin supplements may cause an interference in this assay. Patients may be advised to stop biotin consumption at least 72 hours prior to sample collection.
Immediately following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
- Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
- Freeze
Frozen (preferred) - 14 days
Refrigerated - 14 days
Ambient - 18 hours
Freeze/thaw cycles: stable x 6
- Gross hemolysis
- Gross lipemia
Performance
Electrochemiluminescence Immunoassay (ECLIA); Surface Plasmon Resonance
Clinical and Interpretive info
An interpretive report will be provided
Billing
82397