All IHC stains will include a positive control tissue

• CD3 labels the majority of T cell NHL
• CD3 is absent from all non-T cell malignancies in the neoplastic population
• CD3 can also react with Purkinje cells of the cerebellum

Submit a formalin-fixed, paraffin-embedded tissue

Formalin-fixed, paraffin-embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• CD3 Reacts with the T cell associated CD3 antigen

Staining pattern

• Cytoplasmic and/or cell surface membrane staining

References

1. Masson et. al.: Antisera Against Epitopes Resistant to Denaturation on T3 (CD3) Antigen Can Detect Reactive and Neoplastic T Cells in Paraffin Embedded Tissue Biopsy Samples; American Journal of Clinical Pathology; 1.