Neurokinin A is a ten amino acid putative transmitter synthesized in the neurons it is present in.  Neurokinin A is a member of the family called Tachykinins which also include Neurokinin B, Substance P, Physalaemin, and Eledoisin.   Neurokinin A shares 6 of 10 peptide homologies with Neurokinin B even though they are produced by different genes.   Neurokinin A is also very similar in structure to Substance P and produces some of the same biological actions as Substance P.  Neurokinin A is a potent bronchoconstrictor.  In the gut, Neurokinin A is produced by the intrinsic enteric nervous system.

• Patient should not be on any medications that affect hypertension, gastrointestinal functions, or pain relievers, if possible, for at least 48 hours prior to specimen collection.

Z-Collection plasma vial/tube Inter Science Institute

1. Spin  within two (2 hours of sample collection
2. Transfer 2.0 mL plasma to a  Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp) 
3. Freeze

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Frozen (strict) - 14 days

Refrigerated - NO

Ambient - NO

• Specimen not collected in Z preservative tube.

Direct Radioimmunoassay (RIA)

< 40 pg/mL